Pulse chase experiments indicated that there was little turnover of the attached myristic acid whereas this was. Pdf cytotoxic potential of nhexadecanoic acid extracted. Unsaturated fatty acids were unable to induce cytokine release from cultured astrocytes. Kinetics of esterification of palmitic acid with ethanol. This study describes the effects of longchain fatty acids on inflammatory signaling in cultured astrocytes. A wide variety of msds palmitic acid options are available to you, such as industrial grade, food grade, and agriculture grade. Palmitic acid revision date 10feb2015 complete information. Furthermore, palmitic acid induces apoptosis in the human leukemic cell line molt4 at 50 microgramsml. Intended use of the product use of the substancemixture. Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms.
Safety data sheet northwest missouri state university. Dha is an omega3 fatty acid, which is a type of 32 polyunsaturated fatty acid pufa with 6 carbon double bonds. The results of ir showed that palm oil contains palmitic acid, stearic acid and oleic acid as the main fatty acid components, however with varying amounts. First aid measures general advice consult a physician. Most important symptoms and effects bothacute and delayed. Find msds or sds, a coa, data sheets and more information. Component freshwater algae freshwater fish microtox water flea palmitic acid not listed 150 mgl lc50 96 h not listed not listed persistence and degradabilityinsoluble in water bioaccumulation accumulationno. Ecological information ecotoxicity do not empty into drains. Palmitic acid 92% fgk 57103 persistence and degradability readily biodegradable in water. Final report on the safety assessment of oleic acid, laurie.
Palmitic acid methyl ester safety data sheet supersedes revision. If breathing is labored seek immediate medical attention. Isps industrial products are used as materials in the production of products by. Palmitic acid is the first fatty acid produced during lipogenesis and from which longer fatty acids can be produced palmitic acid, or hexadecanoic acid is one of the most common saturated fatty acids found in animals and plants. Sds of palmitic acid, safety data sheets, cas 57103. This chemical is considered hazardous by the 2012 osha hazard. Oa is widely used as surfactant for the stabilization of magnetic nanoparticles. This is a very important distinction, because triglycerides are chemically inert molecules that can be stored in very large amounts in cells without causing. It is also the first fatty acid produced during fatty acid synthesis and is the precursor to longer fatty acids. Acme hardesty chemicals msds of stearic acid disclaimer the information presented here is believed to be accurate and pertains only to the product. Generally esterification is carried out in the presence of sulphuric acid as catalyst because of its high acid strength. The amorphous palmitic acid obtained was characterized using infra red ir spectroscopy.
Fatty acid mass spectrometry protocol updated 122010 by aaron armando. Sigmaaldrich offers a number of palmitic acid products. Cycloheximide could prevent the attachment of myristic acid to cell proteins, but only reduced the levels of palmitic acid incorporation. Aluminium salts of palmitic acid and naphthenic acid were combined during world war ii to produce napalm. One molecular target of palmitic acid in tumor cells is dna topoisomerase i, however, interestingly, it does not affect dna topoisomerase ii, conclusions. Palmitic acid doesnt always make its way onto ingredient lists. Refer to section 8 of msds for personal protection details. Palmitic acid can also be found in meats, cheeses, butter, and other dairy products. The palmitate anion is the observed form of palmitic acid at physiologic ph 7. Dietary palmitic acid increases ldlcholesterol grundy and denke, 1990. If inhaled if breathed in, move person into fresh air. Pulse chase experiments indicated that there was little turnover of the attached myristic acid whereas this was significant for covalently bound palmitic acid. Monodisperse magnetite nanoparticles 7 and 19nm coated with oa have been prepared.
As its name indicates, it is a major component of the oil from the fruit of oil palms. Bioaccumulative potential palmitic acid 92% fgk 57103 bioaccumulative potential not established. Palmitic acid 53 to 55% stearic acid 45 to 47% average molecular weight. Chemical product and company identification product name. This compound constitutes about 25% of the fatty acids of beef or pork fat, but only 610% of the fatty acids of sunflower, safflower, peanut, or soy oils see table 6.
Identification of the substancemixture and of the companyundertaking. Many animal and plantbased foods contain palmitic acid, and its actually the most abundant saturated fat acid in your body and plays many essential roles. Palmitic acid msds material safety data sheet or sds, coa and coq, dossiers, brochures and other available documents. Palmitic acid also shows in vivo antitumor activity in mice. But if youve ever bought coconut oil or a product thats made with palm oil, both contain this fatty acid. Palmitic acid or stearic acid t otal, ldl, hdlcholesterol and apo a1 were higher after palmitic acid schwab et al. Safety data sheet according to 29cfr19101200 and ghs rev.
Palmitic acid revision date 10feb2015 reactive hazard no clean water act not applicable clean air act not applicable osha occupational safety and health administration not applicable cercla not applicable california proposition 65 this product does not contain any proposition 65 chemicals state righttoknow not applicable u. Show this safety data sheet to the doctor in attendance. Sep 03, 2019 palmitic acid doesnt always make its way onto ingredient lists. Material safety data sheet west liberty university. India veritas house, 70 mint road, fort, mumbai 400 001. Its quantitative removal from the mixtures of triglyceride and partial glycerides has been reported. Palmitic acid is found naturally in palm oil and palm kernel oil, as well as in butter, cheese, milk and meat. All operating parameters for the instrument are contained in the raw data files, all other conditions are listed here. Cytotoxic potential of nhexadecanoic acid extracted from kigelia pinnata leaves article pdf available in asian journal of cell biology 121. Free fatty acids, including palmitic acid, are not present in animal tissues or in the diet to any large extent. Lauric acid c12 is the main acid in coconut oil 4550 percent and palm kernel oil 4555 percent.
Final report on the safety assessment of oleic acid. Material safety data sheet palmitic acid section 1 chemical product and company identification msds name. Palmitic acid is a saturated longchain fatty acid with a 16 carbon backbone. Extraction and characterization of palmitic acid from palm oil. Industrial, lubricants, personal care, cleaners, detergents, soaps, textile additives, rubber additives. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Palmitates are the salts and esters of palmitic acid. Palmitic acid safety data sheet supersedes revision.
Chinese vegetable tallow is reported to contain 6070% palmitic acid. Palm oil, palmitic acid, fatty acid composition, lypholization, ftir. Saturated long chain fatty acids activate inflammatory. Hexadecanoic acid is a straightchain, sixteen carbon, saturated longchain fatty acid. Not expected to present a significant hazard under anticipated conditions of normal use. Palmitic acid, present at unknown concns, reached 37. Using the warburg test method, palmitic acid, present at 500 ppm, reached 2.